by Clinical Neuropsychologist | Saturday, February 22, 2025 | Dementia
Abstract INTRODUCTION Specific features of subjective cognitive decline (SCD-plus) have been proposed to indicate an increased risk of preclinical Alzheimer’s disease (AD). However, few studies have examined how these features relate to AD biomarkers in...
by Clinical Neuropsychologist | Thursday, February 20, 2025 | Dementia
Abstract Neurodegenerative diseases (NDDs) pose a significant challenge in modern medicine due to their clinical heterogeneity, multifactorial etiologies, and frequent co-pathologies. Traditional diagnostic systems, based on clinical symptoms and post mortem findings,...
by Clinical Neuropsychologist | Wednesday, February 19, 2025 | Dementia
Abstract Recent evidence suggests that ocular testing holds promise as a non-invasive and cost-effective method for the early detection of Alzheimer’s disease (AD). After interviews with neurologists, optometrists, primary care physicians, and ophthalmologists,...
by Clinical Neuropsychologist | Wednesday, February 19, 2025 | Dementia
Abstract INTRODUCTION We examined how abnormal prefrontal neurophysiology and changes in gamma-aminobutyric acid-ergic (GABAergic) neurotransmission contribute to behavioral impairments in disorders associated with frontotemporal lobar degeneration (FTLD). METHODS We...
by Clinical Neuropsychologist | Wednesday, February 19, 2025 | Dementia
Abstract INTRODUCTION Early-onset and late-onset Alzheimer’s disease (EOAD and LOAD, respectively) have distinct clinical manifestations, with prior work based on small samples suggesting unique patterns of neurodegeneration. The current study performed a...