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Explainable Alzheimer’s Disease Detection Using Linguistic Features from Automatic Speech Recognition

by Clinical Neuropsychologist Online | Friday, February 16, 2024 | Dementia

Alzheimer’s disease (AD) is the most prevalent type of dementia and can cause abnormal cognitive function and progressive loss of essential life skills. Early screening is thus necessary for the prevention and intervention of AD. Speech dysfunction is an early onset...

Predicting Alzheimer’s Disease with Interpretable Machine Learning

by Clinical Neuropsychologist Online | Friday, February 16, 2024 | Dementia

This study aimed to develop novel machine learning models for predicting Alzheimer’s disease (AD) and identify key factors for targeted prevention. We included 1,219, 863, and 482 participants aged 60+ years with only sociodemographic, both sociodemographic and...

The dementia care study (D‐CARE): Recruitment strategies and demographic characteristics of participants in a pragmatic randomized trial of dementia care

by Clinical Neuropsychologist Online | Thursday, February 15, 2024 | Dementia

Abstract INTRODUCTION Pragmatic research studies that include diverse dyads of persons living with dementia (PLWD) and their family caregivers are rare. METHODS Community-dwelling dyads were recruited for a pragmatic clinical trial evaluating three approaches to...

Lewy body pathology modifies risk factors for cerebral amyloid angiopathy when comorbid with Alzheimer’s disease pathology

by Clinical Neuropsychologist Online | Wednesday, February 14, 2024 | Dementia

Abstract INTRODUCTION Cerebral amyloid angiopathy (CAA) often accompanies dementia-associated pathologies and is important in the context of anti-amyloid monoclonal therapies and risk of hemorrhage. METHODS We conducted a retrospective neuropathology-confirmed study...

Giving voice to the voiceless: Understanding the perceived needs of dementia family carers in Soweto, a South African township

by Clinical Neuropsychologist Online | Wednesday, February 14, 2024 | Dementia

Dementia, Volume 23, Issue 4, Page 622-642, May 2024. This qualitative study aimed to provide family caregivers with an independent platform to reflect on and identify their needs in the role of dementia caregiver. Thirty caregivers were interviewed using a...
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