by Clinical Neuropsychologist Online | Wednesday, March 5, 2025 | Dementia
Abstract INTRODUCTION The progressive nature of Alzheimer’s disease (AD) highlights the importance of predicting lifetime risk and updating assessments as new data emerge. This study aimed to develop a dynamic model using longitudinal cognitive assessments for...
by Clinical Neuropsychologist Online | Friday, February 28, 2025 | Dementia
Abstract INTRODUCTION Human tau protein, composed of six brain-specific isoforms, is a major driver of Alzheimer’s disease (AD). The role of its isoforms however remains unclear and human AD models are scarce. METHODS We generated human MAPT– (tau–) knockout...
by Clinical Neuropsychologist Online | Thursday, February 27, 2025 | Dementia
Dementia, Ahead of Print. ObjectiveThe study’s aim was to better understand how persons, diagnosed with dementia while still working, strived to make sense of and come to terms with their changing everyday lives during the process of exiting work life.MethodsThe study...
by Clinical Neuropsychologist Online | Wednesday, February 26, 2025 | Dementia
Abstract INTRODUCTION The Clinical Dementia Rating (CDR) Scale is a gold standard for staging impairment in Alzheimer’s disease and other dementias (ADRD). The Quick Dementia Rating System (QDRS) offers similar results in 3 to 5 minutes without a trained...
by Clinical Neuropsychologist Online | Monday, February 24, 2025 | Dementia
Abstract INTRODUCTION Limited data exist on the utility of plasma biomarkers to predict incident abnormal amyloid positron emission tomography (PET). In this study we evaluate the association of plasma Alzheimer’s disease (AD) biomarkers with amyloid PET...
