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Correction to “Head‐to‐head comparison of leading blood tests for Alzheimer’s disease pathology”

by Clinical Neuropsychologist | Tuesday, December 31, 2024 | Dementia

Alzheimer’s &Dementia, EarlyView. If you do not see content above, kindly GO TO SOURCE. Not all publishers encode content in a way that enables republishing at Neuro.vip. This post is Copyright: | December 31, 2024 Wiley: Alzheimer’s & Dementia:...

Roles of blood monocytes carrying TREM2R47H mutation in pathogenesis of Alzheimer’s disease and its therapeutic potential in APP/PS1 mice

by Clinical Neuropsychologist | Tuesday, December 31, 2024 | Dementia

Abstract INTRODUCTION The triggering receptor expressed on myeloid cells 2 (TREM2) arginine-47-histidine (R47H) mutation is a significant risk for Alzheimer’s disease (AD) with unclear mechanisms. Previous studies focused on microglial amyloid-β (Aβ)...

Lactylation of tau in human Alzheimer’s disease brains

by Clinical Neuropsychologist | Tuesday, December 31, 2024 | Dementia

Abstract INTRODUCTION Aggregation of hyperphosphorylated tau (tauopathy) is associated with cognitive impairment in patients with Alzheimer’s disease (AD). In AD, a metabolic shift due to the Warburg effect results in increased lactate production. Lactate can...

Paving the way for Alzheimer’s disease blood‐based biomarkers in primary care

by Clinical Neuropsychologist | Tuesday, December 31, 2024 | Dementia

Abstract Blood-based biomarkers (BBBMs) for Alzheimer’s disease (AD) have the potential to revolutionize the detection and management of cognitive impairment. AD BBBMs are not currently recommended for use in primary care but may soon be as research demonstrates...

Choroid plexus cysts on 7T MRI: Relationship to aging and neurodegenerative diseases

by Clinical Neuropsychologist | Sunday, December 29, 2024 | Dementia

Abstract INTRODUCTION The choroid plexus (CP) may play a crucial role in brain degeneration. We aim to assess whether CP cysts (CPCs), defined using ultra-high field magnetic resonance imaging (MRI), relate to aging and neurodegeneration. METHODS We used...
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