by Clinical Neuropsychologist | Wednesday, December 18, 2024 | Dementia
Abstract INTRODUCTION Placental growth factor (PlGF) may regulate cerebrovascular permeability. We hypothesized that white matter interstitial fluid accumulation, estimated via magnetic resonance imaging (MRI) free water (FW), would explain the associations between...
by Clinical Neuropsychologist | Wednesday, December 18, 2024 | Dementia
Abstract INTRODUCTION We investigated whether early life exposure to state-level structural sexism influenced late-life memory trajectories among United Staes (U.S.) -born women and men and determined whether associations differed between racialized groups. METHODS...
by Clinical Neuropsychologist | Friday, December 13, 2024 | Dementia
Abstract INTRODUCTION Progressive supranuclear palsy (PSP) is a devastating 4R tauopathy affecting motor functions and is often misdiagnosed/underdiagnosed due to a lack of specific biomarkers. Synaptic loss is an eminent feature of tauopathies including PSP. Novel...
by Clinical Neuropsychologist | Tuesday, December 10, 2024 | Dementia
Abstract INTRODUCTION This study investigated the impact of trisomy 21 mosaicism (mT21) on Alzheimer’s disease (AD) neuropathology in a well-characterized clinical case described by Ringman et al. METHODS We describe AD neuropathology in mT21 including amyloid...
by Clinical Neuropsychologist | Tuesday, December 10, 2024 | Dementia
Abstract INTRODUCTION Recommendations for advance care planning (ACP) in persons with cognitive impairment are based on expert input without insight from actual ACP conversations. METHODS We used thematic analysis to analyze transcripts of ACP conversations for 88...
