by Clinical Neuropsychologist | Tuesday, December 31, 2024 | Dementia
Abstract INTRODUCTION Alzheimer’s disease (AD), primary age-related tauopathy (PART), and chronic traumatic encephalopathy (CTE) all feature hyperphosphorylated tau (p-tau)–immunoreactive neurofibrillary degeneration, but differ in neuroanatomical distribution...
by Clinical Neuropsychologist | Tuesday, December 31, 2024 | Dementia
Abstract INTRODUCTION Some individuals show intact cognition despite the presence of neuropathological hallmarks of Alzheimer’s disease (AD). The plasticity of parvalbumin (PV)-containing interneurons might contribute to resilience. Perineuronal nets (PNNs),...
by Clinical Neuropsychologist | Tuesday, December 31, 2024 | Dementia
Alzheimer’s &Dementia, EarlyView. If you do not see content above, kindly GO TO SOURCE. Not all publishers encode content in a way that enables republishing at Neuro.vip. This post is Copyright: Chi‐Kuei Hsu, Chih‐Cheng Lai | December 31, 2024 Wiley:...
by Clinical Neuropsychologist | Tuesday, December 31, 2024 | Dementia
Abstract INTRODUCTION Alzheimer’s disease (AD) shows significant sex differences in prevalence and clinical manifestations, but the underlying molecular mechanisms remain unclear. METHODS This study used a large-scale, single-cell transcriptomic atlas of the...
by Clinical Neuropsychologist | Tuesday, December 31, 2024 | Dementia
Abstract INTRODUCTION White matter hyperintensity volumes (WMHVs) are disproportionally prevalent in individuals with Alzheimer’s disease (AD), potentially reflecting neurovascular injury. We quantify the association between AD polygenic risk score (AD-PRS) and...
