by Clinical Neuropsychologist Online | Friday, January 3, 2025 | Dementia
Abstract Background Alzheimer’s disease (AD) is the leading cause of dementia in elderly humans worldwide. More than 40 million people currently suffer from AD, and this prevalence tends to increase considerably in the coming decades due to increased longevity. The...
by Clinical Neuropsychologist Online | Friday, January 3, 2025 | Dementia
Abstract Ageing changes the adult brain at the molecular, cellular and functional levels, driving regenerative decline, inflammation, cognitive impairments and susceptibility to dementia-related neurodegenerative disorders, such as Alzheimer’s disease (AD). There is...
by Clinical Neuropsychologist Online | Friday, January 3, 2025 | Dementia
Abstract Understanding the physiological connection between platelets and brain function reveals new paradigms in neurodegenerative disease treatment. Platelets, traditionally associated with hemostasis, but also sometimes regarded as a mirror of neurons in the blood...
by Clinical Neuropsychologist Online | Friday, January 3, 2025 | Dementia
Abstract Background Despite significant advancements in the development of blood biomarkers for AD, challenges persist due to the complex interplay of genetic and environmental risk factors in AD pathogenesis. Epigenetic processes, including non-coding RNAs and...
by Clinical Neuropsychologist Online | Thursday, January 2, 2025 | Dementia
Abstract INTRODUCTION Whole genome methylation sequencing (WGMS) in blood identifies differential DNA methylation in persons with late-onset dementia due to Alzheimer’s disease (AD) but has not been tested in persons with mild cognitive impairment (MCI). METHODS...
