by Clinical Neuropsychologist | Tuesday, June 11, 2024 | Dementia
Abstract INTRODUCTION The cognitive impairment patterns and the association with Alzheimer’s disease (AD) in mental disorders remain poorly understood. METHODS We analyzed data from 486,297 UK Biobank participants, categorizing them by mental disorder history to...
by Clinical Neuropsychologist | Tuesday, June 11, 2024 | Dementia
Abstract INTRODUCTION Female-specific reproductive factors and exogeneous estrogen use are associated with cognition in later life. However, the underlying mechanisms are not understood. The present study aimed to investigate the effect of reproductive factors on...
by Clinical Neuropsychologist | Tuesday, June 11, 2024 | Dementia
Abstract INTRODUCTION Most people with Alzheimer’s disease and related dementia (ADRD) also suffer from two or more chronic conditions, known as multiple chronic conditions (MCC). While many studies have investigated the MCC patterns, few studies have considered...
by Clinical Neuropsychologist | Monday, June 10, 2024 | Dementia
Abstract INTRODUCTION The ɛ4 allele of the apolipoprotein E gene (APOE ɛ4) is the strongest genetic risk factor for Alzheimer’s disease (AD), but the mechanisms connecting APOE ɛ4 to AD are not clear. METHODS Participants (n = 596) were from two...
by Clinical Neuropsychologist | Thursday, June 6, 2024 | Dementia
Abstract INTRODUCTION We investigated the effect vigorous physical activity (VPA) on the risk of incident mild cognitive impairment (MCI) and probable dementia among individuals with high-risk hypertension. METHODS Baseline self-reported frequency of VPA was...