by Clinical Neuropsychologist Online | Wednesday, December 18, 2024 | Dementia
Abstract INTRODUCTION We investigated whether early life exposure to state-level structural sexism influenced late-life memory trajectories among United Staes (U.S.) -born women and men and determined whether associations differed between racialized groups. METHODS...
by Clinical Neuropsychologist Online | Friday, December 13, 2024 | Dementia
Abstract INTRODUCTION Progressive supranuclear palsy (PSP) is a devastating 4R tauopathy affecting motor functions and is often misdiagnosed/underdiagnosed due to a lack of specific biomarkers. Synaptic loss is an eminent feature of tauopathies including PSP. Novel...
by Clinical Neuropsychologist Online | Tuesday, December 10, 2024 | Dementia
Abstract INTRODUCTION This study investigated the impact of trisomy 21 mosaicism (mT21) on Alzheimer’s disease (AD) neuropathology in a well-characterized clinical case described by Ringman et al. METHODS We describe AD neuropathology in mT21 including amyloid...
by Clinical Neuropsychologist Online | Tuesday, December 10, 2024 | Dementia
Abstract INTRODUCTION Recommendations for advance care planning (ACP) in persons with cognitive impairment are based on expert input without insight from actual ACP conversations. METHODS We used thematic analysis to analyze transcripts of ACP conversations for 88...
by Clinical Neuropsychologist Online | Tuesday, December 10, 2024 | Dementia
Abstract INTRODUCTION The SORL1 locus exhibits protective effects against Alzheimer’s disease (AD) across ancestries, yet systematic studies in diverse populations are sparse. METHODS Logistic regression identified AD-associated SORL1 haplotypes in East Asian...
