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The role of leukocytes in cognitive impairment due to long‐term exposure to fine particulate matter: A large population‐based mediation analysis

by Clinical Neuropsychologist | Wednesday, October 16, 2024 | Dementia

Abstract INTRODUCTION Our understanding of how fine particulate matter (PM2.5) impacts cognitive functioning is limited. Systemic inflammation processes may play a role in mediating this effect. METHODS This prospective cohort study used data from 66,254 participants...

APOE 𝜀4‐related blood–brain barrier breakdown is associated with microstructural abnormalities

by Clinical Neuropsychologist | Wednesday, October 16, 2024 | Dementia

Abstract INTRODUCTION Blood–brain barrier (BBB) dysfunction occurs in Alzheimer’s disease (AD). Yet, the stage at which it appears along the AD time course and whether it contributes to neurodegeneration remain unclear. METHODS Older adults (61 to 90 years) from...

Artificial intelligence–assisted oculo‐gait measurements for cognitive impairment in cerebral small vessel disease

by Clinical Neuropsychologist | Wednesday, October 16, 2024 | Dementia

Abstract INTRODUCTION Oculomotor and gait dysfunctions are closely associated with cognition. However, oculo-gait patterns and their correlation with cognition in cerebral small vessel disease (CSVD) remain unclear. METHODS Patients with CSVD from a hospital-based...

Association of MIND diet with cognitive decline among Black and White older adults

by Clinical Neuropsychologist | Wednesday, October 16, 2024 | Dementia

Abstract INTRODUCTION We examined the Mediterranean–Dietary Approaches to Stop Hypertension Intervention for Neurodegenerative Delay (MIND) diet’s association with cognitive decline by race among older adults in the Chicago Health and Aging Project. METHODS Five...

Exploring the perceptions of New Zealand Chinese dementia carers on the adapted world health organization iSupport manual: A qualitative study

by Clinical Neuropsychologist | Monday, October 14, 2024 | Dementia

Dementia, Volume 24, Issue 1, Page 133-149, January 2025. BackgroundAcross countries, most dementia carers report a lack of adequate information about dementia and local services. To address this issue, the World Health Organization developed the iSupport programme to...
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