by Clinical Neuropsychologist | Thursday, April 18, 2024 | Dementia
The connection between periodontitis and mild cognitive impairment (MCI) continues to receive attention. However, whether periodontitis is a risk factor for MCI remains still uncertain. This study aims to systematically analyze the available literature regarding the...
by Clinical Neuropsychologist | Wednesday, April 17, 2024 | Dementia
Abstract INTRODUCTION Cerebral small vessel disease (SVD) is a common cause of stroke/vascular dementia with few effective treatments. Neuroinflammation and increased blood-brain barrier (BBB) permeability may influence pathogenesis. In rodent models, minocycline...
by Clinical Neuropsychologist | Wednesday, April 17, 2024 | Dementia
Abstract INTRODUCTION Age-related magnetic resonance imaging (MRI) T2 white matter hyperintensities (WMHs) are common and associated with neurological decline. We investigated the histopathological underpinnings of MRI WMH and surrounding normal appearing white matter...
by Clinical Neuropsychologist | Wednesday, April 17, 2024 | Dementia
Abstract INTRODUCTION In trials of amyloid-lowering drugs for Alzheimer’s disease (AD), differential eligibility may contribute to under-inclusion of racial and ethnic underrepresented groups. We examined plasma amyloid beta 42/40 and positron emission...
by Clinical Neuropsychologist | Tuesday, April 16, 2024 | Dementia
Abstract INTRODUCTION Ozone (O3) is an air pollutant associated with Alzheimer’s disease (AD) risk. The lung–brain axis is implicated in O3-associated glial and amyloid pathobiology; however, the role of disease-associated astrocytes (DAAs) in this process...