by Clinical Neuropsychologist | Friday, October 11, 2024 | Dementia
Abstract INTRODUCTION This study examines the role of lifestyle factors in cognitive reserve among older adults, focusing on the moderating effect of apolipoprotein E (APOE) ε4 status. METHODS Data from 157 participants aged 45 and older from the Healthy Brain...
by Clinical Neuropsychologist | Friday, October 11, 2024 | Dementia
Abstract INTRODUCTION Microglial responses are an integral part of Alzheimer’s disease (AD) pathology and are associated with amyloid beta (Aβ) deposition. This study aimed to investigate the effects of Aβ and microglial responses on global cognitive impairment....
by Clinical Neuropsychologist | Thursday, October 10, 2024 | Dementia
Abstract INTRODUCTION We evaluated impaired odor identification and global cognition as simple, cost-effective alternatives to neuroimaging biomarkers to predict cognitive decline and dementia in the Mayo Clinic Study of Aging. METHODS Six hundred forty-seven...
by Clinical Neuropsychologist | Wednesday, October 9, 2024 | Dementia
Abstract INTRODUCTION Early detection of both objective and subjective cognitive impairment is important. Subjective complaints in healthy individuals can precede objective deficits. However, the differential associations of objective and subjective cognition with...
by Clinical Neuropsychologist | Tuesday, October 8, 2024 | Dementia
Abstract INTRODUCTION Clinicians lack the tools to incorporate physical activity into clinical care for Alzheimer’s disease prevention. We tested a 52-week exercise and health education program (Lifestyle Empowerment for Alzheimer’s Prevention [LEAP! Rx])...
