by Clinical Neuropsychologist | Tuesday, October 29, 2024 | Dementia
Abstract BACKGROUND The Everyday Cognition scale (ECog-39) scores are associated with future cognitive decline. We investigated whether the 12-item ECog (ECog-12), which is being collected in Alzheimer’s Disease Neuroimaging Initiative (ADNI)4, can predict...
by Clinical Neuropsychologist | Tuesday, October 29, 2024 | Dementia
Abstract INTRODUCTION Not all individuals who experience mild cognitive impairment (MCI) transition through progressive stages of cognitive decline at the same rate, if at all. Previous observational studies have identified the retrosplenial cortex (RSC) as an early...
by Clinical Neuropsychologist | Tuesday, October 29, 2024 | Dementia
Abstract INTRODUCTION People living with dementia are less likely to be admitted to high-rated nursing homes than people without dementia, despite their increased care needs. We investigated the effect of admission to nursing homes with higher staffing ratings on...
by Clinical Neuropsychologist | Friday, October 25, 2024 | Dementia
Abstract BACKGROUND Synaptic and extrasynaptic distribution of N-methyl-D-aspartate receptors (NMDARs) has not been addressed in the brain from Alzheimer´s disease (AD) subjects, despite their contribution to neurodegeneration. METHODS We have developed a protocol to...
by Clinical Neuropsychologist | Thursday, October 24, 2024 | Dementia
Abstract INTRODUCTION Emerging preclinical evidence suggests that semaglutide, a glucagon-like peptide receptor agonist (GLP-1RA) for type 2 diabetes mellitus (T2DM) and obesity, protects against neurodegeneration and neuroinflammation. However, real-world evidence...
