by Clinical Neuropsychologist | Tuesday, October 8, 2024 | Dementia
Abstract INTRODUCTION Alzheimer’s disease (AD) remains a debilitating condition with limited treatments and additional therapeutic targets needed. Identifying AD protective genetic loci may identify new targets and accelerate identification of therapeutic...
by Clinical Neuropsychologist | Sunday, October 6, 2024 | Dementia
Abstract INTRODUCTION Nursing home (NH) residents with Alzheimer’s disease or related dementias (ADRD) are at high risk for hospital transfer. We aimed to (1) describe characteristics and predictors of avoidable transfer of residents with ADRD and (2) explore...
by Clinical Neuropsychologist | Sunday, October 6, 2024 | Dementia
Abstract INTRODUCTION Growing evidence suggests a role for neuroinflammation in Alzheimer’s disease (AD). We investigated complement pathway activity in AD patient cerebrospinal fluid (CSF) and evaluated its modulation by the anti-tau antibody semorinemab....
by Clinical Neuropsychologist | Sunday, October 6, 2024 | Dementia
Abstract A brief history of events surrounding the conceptualization and original implementation of the Alzheimer’s Disease Neuroimaging Initiative (ADNI) as a public–private partnership (PPP) is provided from the perspective of three individuals directly...
by Clinical Neuropsychologist | Sunday, October 6, 2024 | Dementia
Abstract Diagnosing Alzheimer’s disease (AD) poses significant challenges to health care, often resulting in delayed or inadequate patient care. The clinical integration of blood-based biomarkers (BBMs) for AD holds promise in enabling early detection of...
