by Clinical Neuropsychologist Online | Tuesday, November 26, 2024 | Dementia
Abstract INTRODUCTION Alzheimer’s disease (AD) is a highly heritable disease (60%–80%). Amyloid beta (Aβ) 42/40, neurofilament light chain (NfL), and glial fibrillary acidic protein (GFAP) are plasma biomarkers for AD. Clinical biomarker research would be served...
by Clinical Neuropsychologist Online | Monday, November 25, 2024 | Dementia
Abstract INTRODUCTION Despite extensive studies on mixed neuropathologies, data from China are limited. This study aims to fill this gap by analyzing brain samples from Chinese brain banks. METHODS A total of 1142 brains from six Chinese brain banks were examined...
by Clinical Neuropsychologist Online | Saturday, November 23, 2024 | Dementia
Abstract INTRODUCTION Studies have correlated living close to major roads with Alzheimer’s disease (AD) risk. However, the mechanisms responsible for this link remain unclear. METHODS We exposed olfactory mucosa (OM) cells of healthy individuals and AD patients...
by Clinical Neuropsychologist Online | Friday, November 22, 2024 | Dementia
Abstract INTRODUCTION Late-life air pollution exposure is associated with an increased risk for dementia, with this effect exacerbated among apolipoprotein E-4 (ApoE-4) carriers. However, whether midlife occupational exposures likewise influence dementia outcomes, and...
by Clinical Neuropsychologist Online | Friday, November 22, 2024 | Dementia
Abstract INTRODUCTION Idiopathic normal pressure hydrocephalus (iNPH) and cerebral small vessel disease (CVSD) are age-related diseases, but their prevalence and clinical relationship are unclear. METHODS This prospective cohort study enrolled 95 patients with...
