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REAL AD—Validation of a realistic screening approach for early Alzheimer’s disease

by Clinical Neuropsychologist | Monday, September 23, 2024 | Dementia

Abstract Early diagnosis is crucial to treatment success. This is especially relevant for Alzheimer’s disease (AD), with its protracted preclinical phase. Most health care systems do not have the resources to conduct large-scale AD screenings in middle-aged...

Loss of TREM2 diminishes CAA despite an overall increase of amyloid load in Tg‐SwDI mice

by Clinical Neuropsychologist | Monday, September 23, 2024 | Dementia

Abstract INTRODUCTION The microglial receptor triggering receptor expressed on myeloid cells 2 (TREM2) is a major risk factor for Alzheimer’s disease (AD). Experimentally, Trem2 deficiency affects parenchymal amyloid beta (Aβ) deposition. However, the role of...

Benefits and risks of FDA‐approved amyloid‐targeting antibodies for treatment of early Alzheimer’s disease: Navigating clinician‐patient engagement

by Clinical Neuropsychologist | Sunday, September 22, 2024 | Dementia

Abstract The emergence of the United States Food and Drug Administration (FDA)-approved amyloid-targeting therapies for Alzheimer’s disease challenges clinicians and healthcare providers with a transformative landscape. Effectively communicating the risks,...

‘What are nurses’ and healthcare workers’ cultural understandings of dementia?’ An integrative literature review

by Clinical Neuropsychologist | Saturday, September 21, 2024 | Dementia

Dementia, Volume 24, Issue 3, Page 552-576, April 2025. Aim:to explore the range of cultural understandings of dementia held by people providing nursing care globally.Background:There is a worldwide shortage of nurses and healthcare workers, resulting in extensive...

Safer dementia care spaces: Perspectives from LGBTQ+ people with cognitive impairment and caregivers

by Clinical Neuropsychologist | Thursday, September 19, 2024 | Dementia

Dementia, Volume 24, Issue 2, Page 214-234, February 2025. The number of caregivers and people living with dementia and other related forms of cognitive impairment is increasing worldwide. Compared to heterosexual and cisgender individuals, studies suggest that...
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