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Argentina–Alzheimer’s Disease Neuroimaging Initiative: pioneering Alzheimer’s Research in Latin America and its Implications for Regional Advancement

by Clinical Neuropsychologist | Sunday, October 6, 2024 | Dementia

Abstract The Alzheimer’s Disease Neuroimaging Initiative (ADNI) has fostered collaboration among researchers around the world, catalyzing innovation and accelerating progress in the field. In Latin America, this initiative advanced the validation and development...

Neuronal hypofunction and network dysfunction in a mouse model at an early stage of tauopathy

by Clinical Neuropsychologist | Sunday, October 6, 2024 | Dementia

Abstract INTRODUCTION It is unclear how early neuronal deficits occur in tauopathies, if these are associated with changes in neuronal network activity, and if they can be alleviated with therapies. METHODS To address this, we performed in vivo two-photon Ca2+ imaging...

Regional variation in diagnostic intensity of dementia among older US adults: An observational study

by Clinical Neuropsychologist | Sunday, October 6, 2024 | Dementia

Alzheimer’s &Dementia, EarlyView. If you do not see content above, kindly GO TO SOURCE. Not all publishers encode content in a way that enables republishing at Neuro.vip. This post is Copyright: Xinyue Yang, Man Yin, Zhiqiang Zhang | October 6, 2024 Wiley:...

Salience network segregation mediates the effect of tau pathology on mild behavioral impairment

by Clinical Neuropsychologist | Friday, October 4, 2024 | Dementia

Abstract INTRODUCTION A recently developed mild behavioral impairment (MBI) diagnostic framework standardizes the early characterization of neuropsychiatric symptoms in older adults. However, the joint contributions of Alzheimer’s disease (AD) pathology and...

Widespread transposable element dysregulation in human aging brains with Alzheimer’s disease

by Clinical Neuropsychologist | Wednesday, October 2, 2024 | Dementia

Abstract Introduction Transposable element (TE) dysregulation is associated with neuroinflammation in Alzheimer’s disease (AD) brains. Yet, TE quantitative trait loci (teQTL) have not been well characterized in human aged brains with AD. Methods We leveraged...
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