by Clinical Neuropsychologist Online | Friday, October 11, 2024 | Dementia
Abstract INTRODUCTION Microglial responses are an integral part of Alzheimer’s disease (AD) pathology and are associated with amyloid beta (Aβ) deposition. This study aimed to investigate the effects of Aβ and microglial responses on global cognitive impairment....
by Clinical Neuropsychologist Online | Thursday, October 10, 2024 | Dementia
Abstract INTRODUCTION We evaluated impaired odor identification and global cognition as simple, cost-effective alternatives to neuroimaging biomarkers to predict cognitive decline and dementia in the Mayo Clinic Study of Aging. METHODS Six hundred forty-seven...
by Clinical Neuropsychologist Online | Wednesday, October 9, 2024 | Dementia
Abstract INTRODUCTION Early detection of both objective and subjective cognitive impairment is important. Subjective complaints in healthy individuals can precede objective deficits. However, the differential associations of objective and subjective cognition with...
by Clinical Neuropsychologist Online | Tuesday, October 8, 2024 | Dementia
Abstract INTRODUCTION Clinicians lack the tools to incorporate physical activity into clinical care for Alzheimer’s disease prevention. We tested a 52-week exercise and health education program (Lifestyle Empowerment for Alzheimer’s Prevention [LEAP! Rx])...
by Clinical Neuropsychologist Online | Tuesday, October 8, 2024 | Dementia
Abstract INTRODUCTION Alzheimer’s disease (AD) remains a debilitating condition with limited treatments and additional therapeutic targets needed. Identifying AD protective genetic loci may identify new targets and accelerate identification of therapeutic...
