by Clinical Neuropsychologist | Wednesday, August 14, 2024 | Dementia
Abstract The goal of the Biostatistics Core of the Alzheimer’s Disease Neuroimaging Initiative (ADNI) has been to ensure that sound study designs and statistical methods are used to meet the overall goals of ADNI. We have supported the creation of a...
by Clinical Neuropsychologist | Wednesday, August 14, 2024 | Dementia
Abstract The Alzheimer’s Disease Neuroimaging Initiative (ADNI) has revolutionized the landscape of Alzheimer’s research through its Informatics Core, which has facilitated unprecedented data standardization and sharing. Over 20 years, ADNI established a...
by Clinical Neuropsychologist | Wednesday, August 14, 2024 | Dementia
Abstract Black women are sorely underrepresented in studies of Alzheimer’s disease and related dementias (ADRD) despite higher rates of ADRD diagnoses than in non-Hispanic White women. There are many reasons for underrepresentation, including medical mistrust,...
by Clinical Neuropsychologist | Wednesday, August 14, 2024 | Dementia
Abstract INTRODUCTION Brain glucose hypometabolism, indexed by the fluorodeoxyglucose positron emission tomography ([18F]FDG-PET) imaging, is a metabolic signature of Alzheimer’s disease (AD). However, the underlying biological pathways involved in these...
by Clinical Neuropsychologist | Wednesday, August 14, 2024 | Dementia
Abstract INTRODUCTION The incidence of Alzheimer’s disease (AD) and obesity rise concomitantly. This study examined whether factors affecting metabolism, race/ethnicity, and sex are associated with AD development. METHODS The analyses included patients ≥ 65...