by Clinical Neuropsychologist | Wednesday, August 14, 2024 | Dementia
Abstract INTRODUCTION Well-chosen biomarkers have the potential to increase the efficiency of clinical trials and drug discovery and should show good precision as well as clinical validity. METHODS We suggest measures that operationalize these criteria and describe a...
by Clinical Neuropsychologist | Tuesday, August 13, 2024 | Dementia
Abstract BACKGROUND Education influences brain health and dementia. However, its impact across regions, specifically Latin America (LA) and the United States (US), is unknown. METHODS A total of 1412 participants comprising controls, patients with Alzheimer’s...
by Clinical Neuropsychologist | Tuesday, August 13, 2024 | Dementia
Abstract INTRODUCTION In this study, we investigated biomarkers in a midlife, racially diverse, at-risk cohort to facilitate early identification and intervention. We examined neuroimaging measures, including resting state functional magnetic resonance imaging (fMRI),...
by Clinical Neuropsychologist | Tuesday, August 13, 2024 | Dementia
Abstract INTRODUCTION Abdominal adipose tissue (AT) mass has adverse effects on the brain. This study aimed to investigate the effect of glucose uptake by abdominal AT on brain aging. METHODS Three-hundred twenty-five participants underwent total-body positron...
by Clinical Neuropsychologist | Tuesday, August 13, 2024 | Dementia
Abstract The Alzheimer’s Disease Neuroimaging Initiative (ADNI) Clinical Core is responsible for coordination of all clinical activities at the ADNI sites, including project management, regulatory oversight, and site management and monitoring, as well as the...
