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Loss of TREM2 diminishes CAA despite an overall increase of amyloid load in Tg‐SwDI mice

by Clinical Neuropsychologist Online | Monday, September 23, 2024 | Dementia

Abstract INTRODUCTION The microglial receptor triggering receptor expressed on myeloid cells 2 (TREM2) is a major risk factor for Alzheimer’s disease (AD). Experimentally, Trem2 deficiency affects parenchymal amyloid beta (Aβ) deposition. However, the role of...

Benefits and risks of FDA‐approved amyloid‐targeting antibodies for treatment of early Alzheimer’s disease: Navigating clinician‐patient engagement

by Clinical Neuropsychologist Online | Sunday, September 22, 2024 | Dementia

Abstract The emergence of the United States Food and Drug Administration (FDA)-approved amyloid-targeting therapies for Alzheimer’s disease challenges clinicians and healthcare providers with a transformative landscape. Effectively communicating the risks,...

‘What are nurses’ and healthcare workers’ cultural understandings of dementia?’ An integrative literature review

by Clinical Neuropsychologist Online | Saturday, September 21, 2024 | Dementia

Dementia, Volume 24, Issue 3, Page 552-576, April 2025. Aim:to explore the range of cultural understandings of dementia held by people providing nursing care globally.Background:There is a worldwide shortage of nurses and healthcare workers, resulting in extensive...

Safer dementia care spaces: Perspectives from LGBTQ+ people with cognitive impairment and caregivers

by Clinical Neuropsychologist Online | Thursday, September 19, 2024 | Dementia

Dementia, Volume 24, Issue 2, Page 214-234, February 2025. The number of caregivers and people living with dementia and other related forms of cognitive impairment is increasing worldwide. Compared to heterosexual and cisgender individuals, studies suggest that...

Partners in progress: Advancing dementia research through collaboration

by Clinical Neuropsychologist Online | Wednesday, September 18, 2024 | Dementia

Dementia, Volume 24, Issue 1, Page 14-22, January 2025. The lived experience of dementia, the views of the caregiver, and the pursuit of scientific understanding by researchers need to converge for holistic and collaborative action to improve dementia research....
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