by Clinical Neuropsychologist | Thursday, August 8, 2024 | Dementia
Abstract INTRODUCTION Whether brain functional connectivity (FC) is consistently disrupted in individuals with mild cognitive impairment (MCI) with isolated language impairment (ilMCI), and its potential to differentiate between MCI subtypes remains uncertain. METHODS...
by Clinical Neuropsychologist | Wednesday, August 7, 2024 | Dementia
Abstract BACKGROUND Subjective cognitive decline (SCD) has been recognized as a potential risk stage for progression to Alzheimer’s disease (AD), while glymphatic dysfunction is considered an important characteristic of AD. We hypothesize that glymphatic...
by Clinical Neuropsychologist | Wednesday, August 7, 2024 | Dementia
Abstract The Alzheimer’s Disease Neuroimaging Initiative (ADNI) PET Core has evolved over time, beginning with positron emission tomography (PET) imaging of a subsample of participants with [18F]fluorodeoxyglucose (FDG)-PET, adding tracers for measurement of...
by Clinical Neuropsychologist | Tuesday, August 6, 2024 | Dementia
Abstract Recent approvals of amyloid immunotherapy drugs for early Alzheimer’s disease (AD) have been highly controversial. In this piece, we consider challenges from the clinical, population health, and health systems perspectives to the role that the new AD...
by Clinical Neuropsychologist | Tuesday, August 6, 2024 | Dementia
Dementia, Volume 23, Issue 8, Page 1263-1291, November 2024. BackgroundCaring for a person with dementia can be a challenging experience, often associated with chronic stress and a heavy burden on family caregivers. Dementia also impacts the relationship between the...
