by Clinical Neuropsychologist | Friday, December 19, 2025 | Neuroimaging
ABSTRACT Background and Purpose Diffusion-weighted imaging (DWI) is the gold standard for assessing ischemic core in acute stroke but may overestimate irreversible injury due to its assumption of Gaussian diffusion. Diffusion kurtosis imaging (DKI), which accounts for...
by Clinical Neuropsychologist | Wednesday, December 17, 2025 | Neuroimaging
ABSTRACT Background and Purpose Amygdala dysfunction is implicated in major depressive disorder. Despite wide acknowledgement of its heterogeneity, the amygdala is predominantly considered as a single entity and functional connectivity investigations have reported...
by Clinical Neuropsychologist | Monday, December 1, 2025 | Neuroimaging
ABSTRACT Background and Purpose Neuromelanin-sensitive magnetic resonance imaging (NM-MRI) is an emerging noninvasive biomarker of catecholaminergic neurons. It assesses neuromelanin-rich regions such as the substantia nigra pars compacta (SNc) and locus coeruleus...
by Clinical Neuropsychologist | Monday, December 1, 2025 | Neuroimaging
ABSTRACT Neurodegeneration with brain iron accumulation (NBIA) refers to a group of rare genetic disorders characterized by abnormal iron deposition in the basal ganglia and brainstem due to impaired iron homeostasis. Disease severity and manifestations vary according...
by Clinical Neuropsychologist | Saturday, November 29, 2025 | Neuroimaging
ABSTRACT Background and Purpose Idiopathic normal pressure hydrocephalus (iNPH) is a neurological disorder that primarily affects older adults and is typically characterized clinically by a triad of symptoms: gait disturbance, urinary urgency or incontinence, and...
