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Spatial reasoning via recurrent neural dynamics in mouse retrosplenial cortex

by Clinical Neuropsychologist Online | Friday, June 6, 2025 | Neuroscience

Nature Neuroscience, Published online: 06 June 2025; doi:10.1038/s41593-025-01944-zUsing a spatial reasoning task in mice, the authors show that retrosplenial cortex encodes spatial hypotheses with well-behaved recurrent dynamics, which can combine these hypotheses...

Noninvasive reduction of neural rigidity alters autistic behaviors in humans

by Clinical Neuropsychologist Online | Friday, June 6, 2025 | Neuroscience

Nature Neuroscience, Published online: 06 June 2025; doi:10.1038/s41593-025-01961-yAutism is associated with inflexibility of brain dynamics. Watanabe and Yamasue show that TMS over the right superior parietal lobule while the brain is ‘stuck’ in a certain state...

Homeostasis of a representational map in the neocortex

by Clinical Neuropsychologist Online | Thursday, June 5, 2025 | Neuroscience

Nature Neuroscience, Published online: 05 June 2025; doi:10.1038/s41593-025-01982-7This study investigates how homeostatic mechanisms endow sensory representations in the auditory cortex with resilience against neuron loss. The map of sounds has the ability to recover...

The brain creates action-based maps of the world near the body

by Clinical Neuropsychologist Online | Thursday, June 5, 2025 | Neuroscience

Nature Neuroscience, Published online: 05 June 2025; doi:10.1038/s41593-025-01959-6Certain neurons have visual and auditory receptive fields anchored to body parts. We show that these neurons reflect the value of interacting with objects near the body, not just their...

RNA dysregulation impairs stress resilience in aged neurons

by Clinical Neuropsychologist Online | Thursday, June 5, 2025 | Neuroscience

Nature Neuroscience, Published online: 05 June 2025; doi:10.1038/s41593-025-01953-yAging is a primary risk factor for neurodegenerative diseases. This study shows that key RNA pathways are disrupted in old neurons, including splicing and the stress response. Because...
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