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An RNA editing strategy rescues gene duplication in a mouse model of MECP2 duplication syndrome and nonhuman primates

by Clinical Neuropsychologist Online | Thursday, December 12, 2024 | Neuroscience

Nature Neuroscience, Published online: 12 December 2024; doi:10.1038/s41593-024-01838-6Duplication of the MECP2 gene (encoding methyl-CpG-binding protein 2) causes MECP2 duplication syndrome. Here the authors develop a Cas13Y system capable of targeting the MECP2 mRNA...

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by Clinical Neuropsychologist Online | Thursday, December 12, 2024 | Neuroscience

If you do not see content above, kindly GO TO SOURCE. Not all publishers encode content in a way that enables republishing at Neuro.vip. This post is Copyright: | December 12, 2024 Journal of Neuroscience current issue Previous Page

Acknowledgment of Reviewers

by Clinical Neuropsychologist Online | Thursday, December 12, 2024 | Neuroscience

If you do not see content above, kindly GO TO SOURCE. Not all publishers encode content in a way that enables republishing at Neuro.vip. This post is Copyright: | December 12, 2024 Journal of Neuroscience current issue Previous Page

Microglia as hunters or gatherers of brain synapses

by Clinical Neuropsychologist Online | Wednesday, December 11, 2024 | Neuroscience

Nature Neuroscience, Published online: 11 December 2024; doi:10.1038/s41593-024-01818-wHow microglia sculpt brain circuits is not clear. Here, the authors propose that their contribution to synapse removal may occur by severing synapses (culling) or collecting...

Stepwise molecular specification of excitatory synapse diversity onto cerebellar Purkinje cells

by Clinical Neuropsychologist Online | Tuesday, December 10, 2024 | Neuroscience

Nature Neuroscience, Published online: 10 December 2024; doi:10.1038/s41593-024-01826-wBrain function requires the formation of diverse and specific synapses. The authors show that the molecular code specifying excitatory connectivity on Purkinje cells evolves in an...
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