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Human thalamocortical structural connectivity develops in line with a hierarchical axis of cortical plasticity

by Clinical Neuropsychologist Online | Friday, July 4, 2025 | Neuroscience

Nature Neuroscience, Published online: 04 July 2025; doi:10.1038/s41593-025-01991-6Sydnor et al. developed a new tractography atlas of thalamocortical structural connections and applied it to three youth samples. They uncovered coordinated development between thalamic...

Addressing artifactual bias in large, automated MRI analyses of brain development

by Clinical Neuropsychologist Online | Tuesday, July 1, 2025 | Neuroscience

Nature Neuroscience, Published online: 01 July 2025; doi:10.1038/s41593-025-01990-7As large-scale neurodevelopmental MRI studies gain prominence, the authors identify tradeoffs between sample size and quality control that can dramatically affect results, and they...

Exploring Auditory Interconnectivity One Sound at a Time

by Clinical Neuropsychologist Online | Tuesday, July 1, 2025 | Neuroscience

As the summer lawn mowers roar outside my window, I cannot help but think about how that sound is being processed in my brain. Like many people, I think about the process as quite hierarchical – with the auditory nerve in my ear registering the sound and then...

Human CLOCK enhances neocortical function

by Clinical Neuropsychologist Online | Monday, June 30, 2025 | Neuroscience

Nature Neuroscience, Published online: 30 June 2025; doi:10.1038/s41593-025-01993-4Regulation of gene expression is a facet of human brain specialization. Here, the authors show that human-like expression of the CLOCK gene in the mouse neocortex enhances cognitive...

Fine-mapping genomic loci refines bipolar disorder risk genes

by Clinical Neuropsychologist Online | Wednesday, June 25, 2025 | Neuroscience

Nature Neuroscience, Published online: 25 June 2025; doi:10.1038/s41593-025-01998-zThis study used fine-mapping to analyze genetic regions associated with bipolar disorder, identifying specific risk genes and providing new insights into the biology of the condition...
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