by Clinical Neuropsychologist Online | Thursday, September 19, 2024 | Neuroscience
Millisecond-scale temporal spiking patterns encode sensory information in the periphery, but their role in the neocortex remains controversial. The sense of touch provides a window into temporal coding because tactile neurons often exhibit precise, repeatable, and...
by Clinical Neuropsychologist Online | Wednesday, September 18, 2024 | Neuroscience
Nature Neuroscience, Published online: 18 September 2024; doi:10.1038/s41593-024-01753-wEarly in Alzheimer’s disease (AD), brain blood flow is reduced by pericytes constricting capillaries. Korte et al. show that oral nimodipine can reverse this and decrease brain...
by Clinical Neuropsychologist Online | Wednesday, September 18, 2024 | Neuroscience
Nature Neuroscience, Published online: 18 September 2024; doi:10.1038/s41593-024-01757-6ApoE4 is a risk factor for Alzheimer’s disease and vascular dementia. We report that in ApoE4 mice perivascular macrophages are the sole source and effectors of the ApoE4 mediating...
by Clinical Neuropsychologist Online | Wednesday, September 18, 2024 | Neuroscience
Nature Neuroscience, Published online: 18 September 2024; doi:10.1038/s41593-024-01763-8Gallego-Rudolf et al. report accelerated brain activity with initial amyloid-β deposition in asymptomatic individuals. In those where tau also starts accumulating, brain activity...
by Clinical Neuropsychologist Online | Tuesday, September 17, 2024 | Neuroscience
Nature Neuroscience, Published online: 17 September 2024; doi:10.1038/s41593-024-01758-5This study shows that the brain can link action to value through neural population subspaces, balancing reliable binding of action to value and generalization to novel stimuli. If...
