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A feature-specific prediction error model explains dopaminergic heterogeneity

by Clinical Neuropsychologist Online | Wednesday, July 3, 2024 | Neuroscience

Nature Neuroscience, Published online: 03 July 2024; doi:10.1038/s41593-024-01689-1The authors present a feature-specific prediction error model that explains heterogeneity in dopaminergic signals within and across projection-defined populations. Model-derived...

Central nervous system-associated macrophages modulate the immune response following stroke in aged mice

by Clinical Neuropsychologist Online | Wednesday, July 3, 2024 | Neuroscience

Nature Neuroscience, Published online: 03 July 2024; doi:10.1038/s41593-024-01695-3How aging influences peripheral immune cell infiltration and the role of these cells following traumatic injury of the CNS is unclear. Here, the authors show that aging transforms...

Constraints on the subsecond modulation of striatal dynamics by physiological dopamine signaling

by Clinical Neuropsychologist Online | Wednesday, July 3, 2024 | Neuroscience

Nature Neuroscience, Published online: 03 July 2024; doi:10.1038/s41593-024-01699-zThe role of dopaminergic neurons in modulating striatal dynamics on subsecond timescales remains unclear. Long, Lee et al. show that only potentially supra-physiological dopamine levels...

Direct neuronal reprogramming of mouse astrocytes is associated with multiscale epigenome remodeling and requires Yy1

by Clinical Neuropsychologist Online | Tuesday, July 2, 2024 | Neuroscience

Nature Neuroscience, Published online: 02 July 2024; doi:10.1038/s41593-024-01677-5The molecular mechanisms underlying direct neuronal reprogramming are unclear. Here the authors show Ngn2-mediated chromatin remodeling and its binding sites underlying mouse...

Neural representation of human experimenters in the bat hippocampus

by Clinical Neuropsychologist Online | Tuesday, July 2, 2024 | Neuroscience

Nature Neuroscience, Published online: 02 July 2024; doi:10.1038/s41593-024-01690-8Snyder et al. report that hippocampal neurons in Egyptian fruit bats modulate their activity depending on the position and identity of human experimenters when bats are flying and...
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