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Single-cell epigenomic reconstruction of developmental trajectories from pluripotency in human neural organoid systems

by Clinical Neuropsychologist Online | Monday, June 24, 2024 | Neuroscience

Nature Neuroscience, Published online: 24 June 2024; doi:10.1038/s41593-024-01652-0The mechanisms underlying human cell diversity are unclear. Here the authors provide a single-cell epigenome map of human neural organoid development and dissect how epigenetic changes...

A high-density 1,024-channel probe for brain-wide recordings in non-human primates

by Clinical Neuropsychologist Online | Monday, June 24, 2024 | Neuroscience

Nature Neuroscience, Published online: 24 June 2024; doi:10.1038/s41593-024-01692-6A probe incorporating 1,024 simultaneously recorded channels with shank length up to 90 mm exhibits high chronic recording stability and enables brain-wide large-scale neural population...

Derivation and transcriptional reprogramming of border-forming wound repair astrocytes after spinal cord injury or stroke in mice

by Clinical Neuropsychologist Online | Friday, June 21, 2024 | Neuroscience

Nature Neuroscience, Published online: 21 June 2024; doi:10.1038/s41593-024-01684-6The features of astrocytes surrounding CNS lesions are unclear. Here the authors show that after spinal cord injury or stroke in mice, mature astrocytes dedifferentiate, proliferate and...

Astrocytes at the border of repair

by Clinical Neuropsychologist Online | Friday, June 21, 2024 | Neuroscience

Nature Neuroscience, Published online: 21 June 2024; doi:10.1038/s41593-024-01670-yAstrocytes have important roles in the repair of the CNS. However, the underlying mechanisms involved remain incompletely understood. O’Shea et al. report that the functional...

Author Correction: A shifting role of thalamocortical connectivity in the emergence of cortical functional organization

by Clinical Neuropsychologist Online | Friday, June 21, 2024 | Neuroscience

Nature Neuroscience, Published online: 21 June 2024; doi:10.1038/s41593-024-01707-2Author Correction: A shifting role of thalamocortical connectivity in the emergence of cortical functional organization If you do not see content above, kindly GO TO SOURCE. Not all...
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