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Poloxamer 188 alleviates cerebral ischemia-reperfusion injury in mice by reducing mitochondrial and lysosomal membrane damage

by Clinical Neuropsychologist | Wednesday, July 16, 2025 | Neuroscience

Objectives: To explore the beneficial effects and mechanisms of Poloxamer 188 (P188) in mitigating cerebral ischemia-reperfusion (I/R) injury in mice. Methods: This study was conducted from 2020 to 2022. Neurological function, brain water content, and infarct size...

Stiripentol safety profile and efficacy in cases of SCN1A-related Dravet syndrome, multi-center experience, Saudi Arabia

by Clinical Neuropsychologist | Wednesday, July 16, 2025 | Neuroscience

Objectives: To evaluate the effectiveness and safety of Stiripentol (STP) in individuals with Dravet syndrome resulting from SCN1A gene mutation Methods: A retrospective study with a descriptive focus was carried out in 2023, involving 44 patients diagnosed with...

Factors affecting rehabilitation participation in patients with spinal cord injury

by Clinical Neuropsychologist | Wednesday, July 16, 2025 | Neuroscience

Objectives: To investigate the factors affecting participation in rehabilitation in patients with spinal cord injury. Methods: Our prospective clinical follow-up study included 87 patients with spinal cord injuries who were hospitalized in a tertiary Physical Therapy...

The prevalence of work-related burnout among neurosurgeons in Saudi Arabia: A multicenter cross-sectional study

by Clinical Neuropsychologist | Wednesday, July 16, 2025 | Neuroscience

Objectives: To evaluate the prevalence of work-related burnout among neurosurgeons at multiple neurosurgical centers in Riyadh, Kingdom of Saudi Arabia. Methods: A cross-sectional study was undertaken involving neurosurgeons in Saudi Arabia. From June 2023, to...

Detection of venous angiomas on susceptibility enhanced magnetic resonance imaging in patients with seizures

by Clinical Neuropsychologist | Wednesday, July 16, 2025 | Neuroscience

Objectives: To evaluate the use of susceptibility-enhanced sequence with conventional magnetic resonance imaging (MRI) of the brain for identification of venous angiomas in epilepsy work up. Methods: A record-based study was performed retrospectively in Radiology...
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