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Dopamine projections to the basolateral amygdala drive the encoding of identity-specific reward memories

by Clinical Neuropsychologist Online | Friday, February 23, 2024 | Neuroscience

Nature Neuroscience, Published online: 23 February 2024; doi:10.1038/s41593-024-01586-7Sias et al. show that dopamine projections to the basolateral amygdala drive the reward learning that supports the predictions and inferences needed for adaptive decision-making. If...

Blood–brain barrier disruption and sustained systemic inflammation in individuals with long COVID-associated cognitive impairment

by Clinical Neuropsychologist Online | Thursday, February 22, 2024 | Neuroscience

Nature Neuroscience, Published online: 22 February 2024; doi:10.1038/s41593-024-01576-9Long COVID is a major public health issue since 2020 and exhibits frequent neurological symptoms. Greene et al. propose that brain fog results from leaky brain blood vessels and a...

Mapping dysfunctional circuits in the frontal cortex using deep brain stimulation

by Clinical Neuropsychologist Online | Thursday, February 22, 2024 | Neuroscience

Nature Neuroscience, Published online: 22 February 2024; doi:10.1038/s41593-024-01570-1Hollunder et al. identify networks where deep brain stimulation reduces symptoms for Parkinson’s disease, Tourette’s syndrome, dystonia and obsessive-compulsive disorder. This...

Leaky blood–brain barrier in long-COVID-associated brain fog

by Clinical Neuropsychologist Online | Thursday, February 22, 2024 | Neuroscience

Nature Neuroscience, Published online: 22 February 2024; doi:10.1038/s41593-024-01577-8Long COVID has remained an on-going public health issue in the years following the global pandemic. Here, we report blood–brain barrier disruption in patients with acute SARS-CoV-2...

Mapping the dysfunctome provides an avenue for targeted brain circuit therapy

by Clinical Neuropsychologist Online | Thursday, February 22, 2024 | Neuroscience

Nature Neuroscience, Published online: 22 February 2024; doi:10.1038/s41593-024-01572-zBrain connections modulated by 534 deep-brain-stimulation electrodes revealed a gradient of circuits involved in dystonia, Parkinson’s disease, Tourette’s syndrome and...
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