by Clinical Neuropsychologist Online | Thursday, February 22, 2024 | Neuroscience
SCN2A encodes NaV1.2, an excitatory neuron voltage-gated sodium channel and a major monogenic cause of neurodevelopmental disorders, including developmental and epileptic encephalopathies (DEE) and autism. Clinical presentation and pharmocosensitivity vary with the...
by Clinical Neuropsychologist Online | Thursday, February 22, 2024 | Neuroscience
The medial nucleus of the trapezoid body (MNTB) has been intensively investigated as a primary source of inhibition in brainstem auditory circuitry. MNTB-derived inhibition plays a critical role in the computation of sound location, as temporal features of sounds are...
by Clinical Neuropsychologist Online | Thursday, February 22, 2024 | Neuroscience
Identifying neural correlates of conscious perception is a fundamental endeavor of cognitive neuroscience. Most studies so far have focused on visual awareness along with trial-by-trial reports of task-relevant stimuli, which can confound neural measures of perceptual...
by Clinical Neuropsychologist Online | Tuesday, February 20, 2024 | Neuroscience
Nature Neuroscience, Published online: 20 February 2024; doi:10.1038/s41593-024-01580-zAstrocytes have important roles in disease. However, modulation of their reactive state is challenging. Here the authors present a phenotypic in vitro screening platform they can...
by Clinical Neuropsychologist Online | Friday, February 16, 2024 | Neuroscience
Nature Neuroscience, Published online: 16 February 2024; doi:10.1038/s41593-024-01573-yRadke et al. found an interferon response in the brainstem nuclei of acute COVID-19 that, in addition to the inflammatory reaction, spreads throughout the vascular unit altering...
