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Diving Deeply into Brain Plasticity Through Work with the Sensorimotor Deprived

by Clinical Neuropsychologist Online | Thursday, March 28, 2024 | Neuroscience

CNS 2024 Q&A with Ella Striem-Amit For the last two decades, Ella Striem-Amit has been searching for answers to some of neuroscience’s deepest questions: How does the human brain develop in individuals and what happens when something is missing? Working with...

Long-term in vivo three-photon imaging reveals region-specific differences in healthy and regenerative oligodendrogenesis

by Clinical Neuropsychologist Online | Wednesday, March 27, 2024 | Neuroscience

Nature Neuroscience, Published online: 27 March 2024; doi:10.1038/s41593-024-01613-7Brain region-specific oligodendrocyte population dynamics are unclear. Here the authors implement long-term in vivo three-photon imaging to determine those dynamics in the cortical and...

TREM1 disrupts myeloid bioenergetics and cognitive function in aging and Alzheimer disease mouse models

by Clinical Neuropsychologist Online | Wednesday, March 27, 2024 | Neuroscience

Nature Neuroscience, Published online: 27 March 2024; doi:10.1038/s41593-024-01610-wThe role of TREM1 in neurodegenerative diseases is unclear. Here the authors show that TREM1 promotes cognitive decline in aging and in the context of amyloid pathology in a mouse...

Xenografted human microglia display diverse transcriptomic states in response to Alzheimer’s disease-related amyloid-β pathology

by Clinical Neuropsychologist Online | Wednesday, March 27, 2024 | Neuroscience

Nature Neuroscience, Published online: 27 March 2024; doi:10.1038/s41593-024-01600-yHuman microglia transplanted in the mouse brain mount a multipronged response to amyloid-β pathology, displaying unique transcriptional states. Alzheimer’s disease risk genes are...

A precision functional atlas of personalized network topography and probabilities

by Clinical Neuropsychologist Online | Tuesday, March 26, 2024 | Neuroscience

Nature Neuroscience, Published online: 26 March 2024; doi:10.1038/s41593-024-01596-5The Masonic Institute for the Developing Brain (MIDB) Precision Brain Atlas is a resource of personalized brain network topographies (n = 9,900). It also provides a probabilistic atlas...
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