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Autism-related traits in myotonic dystrophy type 1 model mice are due to MBNL sequestration and RNA mis-splicing of autism-risk genes

by Clinical Neuropsychologist | Monday, April 21, 2025 | Neuroscience

Nature Neuroscience, Published online: 21 April 2025; doi:10.1038/s41593-025-01943-0Sznajder et al. identified a molecular link between autism and myotonic dystrophy, showing that a tandem repeat mutation in a single gene can disrupt splicing of multiple...

Integrated analysis of molecular atlases unveils modules driving developmental cell subtype specification in the human cortex

by Clinical Neuropsychologist | Monday, April 21, 2025 | Neuroscience

Nature Neuroscience, Published online: 21 April 2025; doi:10.1038/s41593-025-01933-2Nano et al. introduce a pipeline to generate meta-atlases of the human brain from existing single-cell datasets and extract gene modules linked to cell fate specification. Perturbing...

Functionally distinct GABAergic amacrine cell types regulate spatiotemporal encoding in the mouse retina

by Clinical Neuropsychologist | Tuesday, April 15, 2025 | Neuroscience

Nature Neuroscience, Published online: 15 April 2025; doi:10.1038/s41593-025-01935-0GABA is the primary inhibitory neurotransmitter in the central nervous system. Using two-photon GABA imaging, Matsumoto et al. reveal over 40 GABA neuron types in the mouse retina,...

How to Use Your Brain to Make Time Work for You

by Clinical Neuropsychologist | Monday, April 14, 2025 | Neuroscience

Have you ever noticed how time stretches endlessly during a tedious presentation yet passes quickly when you’;re engaged in something exciting? This isn’;t just a trick of the mind, but a process shaped by the brain, and new results show anterior cingulate cortex...

Hippocampal output suppresses orbitofrontal cortex schema cell formation

by Clinical Neuropsychologist | Monday, April 14, 2025 | Neuroscience

Nature Neuroscience, Published online: 14 April 2025; doi:10.1038/s41593-025-01928-zInactivation of the ventral subiculum does not change existing schema cells in the orbitofrontal cortex (OFC) but aids their formation during new learning. This challenges the idea...
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