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Sympathetic and parasympathetic subtypes of body-first Lewy body disease observed in postmortem tissue from prediagnostic individuals

by Clinical Neuropsychologist | Thursday, March 13, 2025 | Neuroscience

Nature Neuroscience, Published online: 13 March 2025; doi:10.1038/s41593-025-01910-9This postmortem study identifies brain-first and two body-first subtypes in prediagnostic cases of Lewy body disease. It highlights sympathetic and parasympathetic pathways in...

Expectation-driven sensory adaptations support enhanced acuity during categorical perception

by Clinical Neuropsychologist | Thursday, March 13, 2025 | Neuroscience

Nature Neuroscience, Published online: 13 March 2025; doi:10.1038/s41593-025-01899-1Bayesian models explain how context biases perceptual behavior toward expected categories, but sensory neurons do not reflect this bias. Instead, expectation sharpens sensory acuity,...

Reply to: A curious concept of CNS clearance

by Clinical Neuropsychologist | Tuesday, March 11, 2025 | Neuroscience

Nature Neuroscience, Published online: 11 March 2025; doi:10.1038/s41593-025-01898-2Reply to: A curious concept of CNS clearance If you do not see content above, kindly GO TO SOURCE. Not all publishers encode content in a way that enables republishing at Neuro.vip....

Study-phase reinstatement predicts subsequent recall

by Clinical Neuropsychologist | Tuesday, March 11, 2025 | Neuroscience

Nature Neuroscience, Published online: 11 March 2025; doi:10.1038/s41593-025-01884-8How can the brain improve memory for an experience after it has occurred? Halpern et al. use intracranial EEG to show that, even while processing current experiences, people reactivate...

Mitochondrial respiratory complex IV deficiency recapitulates amyotrophic lateral sclerosis

by Clinical Neuropsychologist | Tuesday, March 11, 2025 | Neuroscience

Nature Neuroscience, Published online: 11 March 2025; doi:10.1038/s41593-025-01896-4Cheng et al. identify a mitochondrial complex IV (CIV) deficiency in the brains of patients with sporadic amyotrophic lateral sclerosis (ALS). They demonstrate that defects in...
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