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Internal and external codes for location

by Clinical Neuropsychologist | Tuesday, August 26, 2025 | Neuroscience

Nature Neuroscience, Published online: 26 August 2025; doi:10.1038/s41593-025-02045-7When navigating through the world, we can predict our next location on the basis of an internal sense of our location and velocity, but we can also orient to external visual sensory...

CRISPR screening by AAV episome-sequencing (CrAAVe-seq): a scalable cell-type-specific in vivo platform uncovers neuronal essential genes

by Clinical Neuropsychologist | Friday, August 22, 2025 | Neuroscience

Nature Neuroscience, Published online: 22 August 2025; doi:10.1038/s41593-025-02043-9The authors developed an adeno-associated virus-based high-throughput in vivo CRISPR screening platform for endogenous mouse brain cell types. Using this platform, they define genes...

Stable cortical body maps before and after arm amputation

by Clinical Neuropsychologist | Thursday, August 21, 2025 | Neuroscience

Nature Neuroscience, Published online: 21 August 2025; doi:10.1038/s41593-025-02037-7Longitudinal neuroimaging of participants with planned arm amputations shows that the cortical body map remains stable after amputation, with no evidence of hand or face...

Toxoplasma gondii infection and chronic IL-1 elevation drive hippocampal DNA double-strand break signaling, leading to cognitive deficits

by Clinical Neuropsychologist | Thursday, August 21, 2025 | Neuroscience

Nature Neuroscience, Published online: 21 August 2025; doi:10.1038/s41593-025-02041-xChronic brain infection and IL-1 exposure impair spatial memory by triggering DNA double-strand break signaling in hippocampal neurons. Blocking this pathway prevents memory deficits,...

FOXP genes regulate Purkinje cell diversity and cerebellar morphogenesis

by Clinical Neuropsychologist | Monday, August 18, 2025 | Neuroscience

Nature Neuroscience, Published online: 18 August 2025; doi:10.1038/s41593-025-02042-wThe Li lab mapped molecularly distinct Purkinje cell (PC) subtypes in 3D and linked them to adult cerebellar architecture. They found that Foxp1/Foxp2 are essential for PC diversity...
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