by Clinical Neuropsychologist | Monday, August 11, 2025 | Neuroscience
Nature Neuroscience, Published online: 11 August 2025; doi:10.1038/s41593-025-02039-5By selectively isolating and sequencing the rare RNA transcripts containing C9orf72 repeat expansion from ALS–FTD neurons, the authors uncover an alternative splicing mechanism that...
by Clinical Neuropsychologist | Monday, August 11, 2025 | Neuroscience
Nature Neuroscience, Published online: 11 August 2025; doi:10.1038/s41593-025-02040-yThe mechanisms linking neuropsychiatric and metabolic disorders remain unclear. The authors show a pancreas–hippocampus feedback loop whereby metabolic and circadian factors drive...
by Clinical Neuropsychologist | Monday, August 11, 2025 | Neuroscience
Nature Neuroscience, Published online: 11 August 2025; doi:10.1038/s41593-025-02026-wHardcastle and Marshall et al. show that striatal function is domain specific, required for task-related but not spontaneously expressed movements. This functional distinction is...
by Clinical Neuropsychologist | Monday, August 11, 2025 | Neuroscience
Nature Neuroscience, Published online: 11 August 2025; doi:10.1038/s41593-025-02032-yActivation of Gs signaling at mitochondria by mitoDREADD-Gs increases mitochondrial metabolism, leading to better memory in mouse models of dementia, directly linking brain...
by Clinical Neuropsychologist | Wednesday, August 6, 2025 | Neuroscience
Nature Neuroscience, Published online: 06 August 2025; doi:10.1038/s41593-025-02025-xRavenelle et al. show that systematically increasing serotonin has sex-specific effects on fear learning in mice. In females only, increasing serotonin in the BNST enhances fear...
