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Dynamics of glia and neurons regulate homeostatic rest, sleep and feeding behavior in Drosophila

by Clinical Neuropsychologist Online | Monday, April 21, 2025 | Neuroscience

Nature Neuroscience, Published online: 21 April 2025; doi:10.1038/s41593-025-01942-1Animals alternate between active periods and periods of rest or sleep. This study in fruit flies points to brain metabolism as a cause for this and shows that a network of glial cells...

Autism-related traits in myotonic dystrophy type 1 model mice are due to MBNL sequestration and RNA mis-splicing of autism-risk genes

by Clinical Neuropsychologist Online | Monday, April 21, 2025 | Neuroscience

Nature Neuroscience, Published online: 21 April 2025; doi:10.1038/s41593-025-01943-0Sznajder et al. identified a molecular link between autism and myotonic dystrophy, showing that a tandem repeat mutation in a single gene can disrupt splicing of multiple...

Integrated analysis of molecular atlases unveils modules driving developmental cell subtype specification in the human cortex

by Clinical Neuropsychologist Online | Monday, April 21, 2025 | Neuroscience

Nature Neuroscience, Published online: 21 April 2025; doi:10.1038/s41593-025-01933-2Nano et al. introduce a pipeline to generate meta-atlases of the human brain from existing single-cell datasets and extract gene modules linked to cell fate specification. Perturbing...

Functionally distinct GABAergic amacrine cell types regulate spatiotemporal encoding in the mouse retina

by Clinical Neuropsychologist Online | Tuesday, April 15, 2025 | Neuroscience

Nature Neuroscience, Published online: 15 April 2025; doi:10.1038/s41593-025-01935-0GABA is the primary inhibitory neurotransmitter in the central nervous system. Using two-photon GABA imaging, Matsumoto et al. reveal over 40 GABA neuron types in the mouse retina,...

How to Use Your Brain to Make Time Work for You

by Clinical Neuropsychologist Online | Monday, April 14, 2025 | Neuroscience

Have you ever noticed how time stretches endlessly during a tedious presentation yet passes quickly when you’;re engaged in something exciting? This isn’;t just a trick of the mind, but a process shaped by the brain, and new results show anterior cingulate cortex...
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