by Clinical Neuropsychologist | Friday, November 15, 2024 | Neuroscience
Nature Neuroscience, Published online: 15 November 2024; doi:10.1038/s41593-024-01821-1Lee et al. show that the development of the somatotopic map and the tonotopic map for substrate vibration is shaped by the intrinsic distribution of cutaneous end organs and...
by Clinical Neuropsychologist | Friday, November 15, 2024 | Neuroscience
Nature Neuroscience, Published online: 15 November 2024; doi:10.1038/s41593-024-01782-5Brain slices offer an experimental window into human neurophysiology. Using high-density microelectrode array recordings and adeno-associated virus–mediated optogenetics, the...
by Clinical Neuropsychologist | Thursday, November 14, 2024 | Neuroscience
Basolateral amygdala (BLA) neurons are engaged by emotionally salient stimuli. An area of increasing interest is how BLA dynamics relate to evolving reward-seeking behavior, especially under situations of uncertainty or ambiguity. Here, we recorded the activity of...
by Clinical Neuropsychologist | Monday, November 11, 2024 | Neuroscience
Nature Neuroscience, Published online: 11 November 2024; doi:10.1038/s41593-024-01777-2Tyrosine kinase 2 (TYK2) critically regulates tau levels and aggregation by phosphorylating tau’s tyrosine 29. Partial inhibition of TYK2 mitigates tau pathologies in cells and...
by Clinical Neuropsychologist | Monday, November 11, 2024 | Neuroscience
Nature Neuroscience, Published online: 11 November 2024; doi:10.1038/s41593-024-01791-4Using single-nucleus RNA sequencing from 32 donors, researchers identified distinct astrocytic gene expression programs activated across brain regions and Alzheimer’s disease...
