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Astrocyte ensembles manipulated with AstroLight tune cue-motivated behavior

by Clinical Neuropsychologist Online | Monday, February 3, 2025 | Neuroscience

Nature Neuroscience, Published online: 03 February 2025; doi:10.1038/s41593-025-01870-0Using the AstroLight system, the authors reveal that astrocytic ensembles in the nucleus accumbens regulate cue-motivated reward behavior, demonstrating that selective manipulation...

Lynn T. Landmesser (1943–2024)

by Clinical Neuropsychologist Online | Thursday, January 30, 2025 | Neuroscience

Nature Neuroscience, Published online: 30 January 2025; doi:10.1038/s41593-025-01879-5Lynn T. Landmesser, professor emerita of the Department of Neurosciences, School of Medicine at Case Western Reserve University, died on 29 November 2024 at the age of 80. In an...

Oligodendrocytes in Alzheimer’s disease pathophysiology

by Clinical Neuropsychologist Online | Wednesday, January 29, 2025 | Neuroscience

Nature Neuroscience, Published online: 29 January 2025; doi:10.1038/s41593-025-01873-xEmerging evidence highlights the dual role of oligodendrocytes in Alzheimer’s disease, both providing protective mechanisms against the pathology and contributing to its progression....

The architecture of the human default mode network explored through cytoarchitecture, wiring and signal flow

by Clinical Neuropsychologist Online | Tuesday, January 28, 2025 | Neuroscience

Nature Neuroscience, Published online: 28 January 2025; doi:10.1038/s41593-024-01868-0The default mode network (DMN) is implicated in cognition and behavior. Here, the authors show that the DMN is cytoarchitecturally heterogeneous, it contains regions receptive to...

Retrieval of conditioned immune response in male mice is mediated by an anterior–posterior insula circuit

by Clinical Neuropsychologist Online | Monday, January 27, 2025 | Neuroscience

Nature Neuroscience, Published online: 27 January 2025; doi:10.1038/s41593-024-01864-4The authors show that a bidirectional circuit connecting the anterior and posterior (aIC–pIC) insula mediates the conditioned immune response in male mice, illustrating a mechanism...
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