by Clinical Neuropsychologist Online | Thursday, June 27, 2024 | Neuroscience
Nature Neuroscience, Published online: 27 June 2024; doi:10.1038/s41593-024-01673-9Recent studies suggest a close interaction between sensory and motor processes across the neocortex. In this Perspective, Rao proposes active predictive coding as a sensory–motor theory...
by Clinical Neuropsychologist Online | Thursday, June 27, 2024 | Neuroscience
Nature Neuroscience, Published online: 27 June 2024; doi:10.1038/s41593-024-01681-9Using a closed-loop virtual reality system, the authors show that optic flow cues can causally drive and recalibrate the hippocampal place cell system in the absence of an absolute...
by Clinical Neuropsychologist Online | Thursday, June 27, 2024 | Neuroscience
Nature Neuroscience, Published online: 27 June 2024; doi:10.1038/s41593-024-01682-8The involvement of age-related myelin damage in Alzheimer’s disease is unclear. Kedia et al. show that T cell-mediated microglia activation triggers a response against myelinating...
by Clinical Neuropsychologist Online | Wednesday, June 26, 2024 | Dementia
Abstract INTRODUCTION Sequence variants in TMEM106B have been associated with an increased risk of developing dementia. METHODS As part of our efforts to generate a set of mouse lines in which we replaced the mouse Tmem106b gene with a human TMEM106B gene comprised of...
by Clinical Neuropsychologist Online | Wednesday, June 26, 2024 | Dementia
Abstract INTRODUCTION A noncoding variant (rs35349669) within INPP5D , a lipid and protein phosphatase restricted to microglia in the brain, is linked to increased susceptibility to Alzheimer’s disease (AD). While Inpp5d is well-studied in amyloid pathology, its...
