by Clinical Neuropsychologist Online | Monday, February 24, 2025 | Neuroscience
Nature Neuroscience, Published online: 24 February 2025; doi:10.1038/s41593-025-01878-6White matter (WM) astrocytes differ significantly from gray matter astrocytes, with WM astrocytes in the forebrain exhibiting unique proliferation capacity, which is absent in...
by Clinical Neuropsychologist Online | Saturday, February 22, 2025 | Dementia
Abstract INTRODUCTION Isolated REM sleep behavior disorder (iRBD) is a strong prodromal marker of Lewy body diseases (LBDs) – Parkinson’s disease (PD) and dementia with Lewy bodies (DLB). Cholinergic loss is linked to cognitive decline in these conditions, but...
by Clinical Neuropsychologist Online | Saturday, February 22, 2025 | Dementia
Abstract INTRODUCTION Tau positron emission tomography (PET) is a reliable neuroimaging technique for assessing regional load of tau pathology in the brain, but its routine clinical use is limited by cost and accessibility barriers. METHODS We thoroughly investigated...
by Clinical Neuropsychologist Online | Saturday, February 22, 2025 | Dementia
Abstract INTRODUCTION Human herpesvirus (HHV) has been linked to Alzheimer’s disease (AD), but the underlying mechanisms remain unknown. METHODS We leveraged functional genomics data from Religious Orders Study or the Rush Memory and Aging Project (ROS/MAP) and...
by Clinical Neuropsychologist Online | Saturday, February 22, 2025 | Dementia
Abstract Hippocampal atrophy on magnetic resonance imaging is an important biomarker in Alzheimer’s disease (AD). While hippocampal atrophy was thought to result from tau tangles in AD, different neuropathologies can lead to hippocampal atrophy, especially TAR...
