by Clinical Neuropsychologist | Friday, January 17, 2025 | Dementia
Abstract Extracellular vesicles (EVs) have emerged as novel blood-based biomarkers for various pathologies. The development of methods to enrich cell-specific EVs from biofluids has enabled us to monitor difficult-to-access organs, such as the brain, in real time...
by Clinical Neuropsychologist | Friday, January 17, 2025 | Dementia
Abstract INTRODUCTION The plasma proteome’s mediating or moderating roles in the association between poor cardiovascular health (CVH) and brain white matter (WM) microstructural integrity are largely unknown. METHODS Data from 3953 UK Biobank participants were...
by Clinical Neuropsychologist | Friday, January 17, 2025 | Dementia
Abstract INTRODUCTION To examine the longitudinal association between estimated pulse wave velocity (ePWV) and cognitive phenotypes in a rural Chinese older population. METHODS This population-based study included 1857 dementia-free participants (age ≥60 years) who...
by Clinical Neuropsychologist | Friday, January 17, 2025 | Dementia
Abstract INTRODUCTION Visual short-term memory (VSTM) is a critical indicator of Alzheimer’s disease (AD), but whether its neural substrates could adapt to early disease progression and contribute to cognitive resilience in amnestic mild cognitive impairment...
by Clinical Neuropsychologist | Friday, January 17, 2025 | Neuroscience
Nature Neuroscience, Published online: 17 January 2025; doi:10.1038/s41593-024-01863-5Neuronal micronuclei are transferred to microglia during the early postnatal period, which leads to altered microglial morphology and transcriptomic signatures, suggesting that these...
