by Clinical Neuropsychologist Online | Sunday, July 12, 2026 | Dementia
Abstract INTRODUCTION Maintaining social relationships is challenging in advanced old age due to frequent changes in social networks. Little is known about whether social networks are associated with cognitive function, decline, and mortality in this population, or...
by Clinical Neuropsychologist Online | Sunday, July 12, 2026 | Dementia
Abstract BACKGROUND Alzheimer’s disease (AD) occurs primarily as late‑onset (LOAD) and less frequently as early‑onset (EOAD). Its defining pathologies are hyperphosphorylated tau tangles and amyloid beta (Aβ) plaques. METHODS We analyzed the proteomes of 115...
by Clinical Neuropsychologist Online | Sunday, July 12, 2026 | Dementia
Abstract INTRODUCTION Neuropsychiatric symptoms frequently precede Alzheimer’s disease and related dementias, yet risk prediction models typically rely on baseline depression severity or diagnostic status. We examined whether instability in depressive symptoms...
by Clinical Neuropsychologist Online | Sunday, July 12, 2026 | Dementia
Abstract Neurodegenerative diseases are characterized by a loss of neuronal function and structure, often in a region-specific manner. Multiple factors contribute to neuronal dysfunction and death, including pathogenic protein buildup, protein mislocalization, and...
by Clinical Neuropsychologist Online | Sunday, July 12, 2026 | Dementia
Abstract INTRODUCTION Biomarkers for Alzheimer’s disease (AD) are now available for clinical use; however, little is known about their use in primary care. METHODS Cross-sectional analysis of 2024 data from the National Dementia Workforce Study, a nationally...