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Retrieval of conditioned immune response in male mice is mediated by an anterior–posterior insula circuit

by Clinical Neuropsychologist Online | Monday, January 27, 2025 | Neuroscience

Nature Neuroscience, Published online: 27 January 2025; doi:10.1038/s41593-024-01864-4The authors show that a bidirectional circuit connecting the anterior and posterior (aIC–pIC) insula mediates the conditioned immune response in male mice, illustrating a mechanism...

Automation of Ultrasonographic Optic Nerve Sheath Diameter Measurement: A Scoping Review

by Clinical Neuropsychologist Online | Friday, January 24, 2025 | Neuroimaging

ABSTRACT Intracranial pressure (ICP) monitoring is a cornerstone of neurocritical care in managing severe brain injury. However, current invasive ICP monitoring methods carry significant risks, including infection and intracranial hemorrhage, and are contraindicated...

Educational attainment, Aβ, tau, and structural brain reserve in Alzheimer’s disease

by Clinical Neuropsychologist Online | Friday, January 24, 2025 | Dementia

Abstract INTRODUCTION Alzheimer’s disease (AD) patients with higher educational attainment (EA) often exhibit better cognitive function. However, the relationship among EA status, AD pathology, structural brain reserve, and cognitive decline requires further...

Polygenic risk discriminates Lewy body dementia from Alzheimer’s disease

by Clinical Neuropsychologist Online | Friday, January 24, 2025 | Dementia

Abstract INTRODUCTION Lewy body dementia (LBD) shares genetic risk factors with Alzheimer’s disease (AD), including apolipoprotein E (APOE), but is distinguishable at the genome-wide level. Polygenic risk scores (PRS) may therefore improve diagnostic...

Reimagining André Rey’s method for recording the copy process of the Rey Complex Figure Test: A commentary

by Clinical Neuropsychologist Online | Friday, January 24, 2025 | Neuropsychology (general)

Abstract In 1941, André Rey published the Rey Complex Figure, a widely used test for assessing visual-constructional ability and visual memory. It consists of two parts: copy and recall. Evaluating the copy portion presents challenges, as it requires the administrator...
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