by Clinical Neuropsychologist Online | Thursday, November 21, 2024 | Neuroscience
Nature Neuroscience, Published online: 21 November 2024; doi:10.1038/s41593-024-01722-3The cerebral cortex shows complex organization across diverse biological scales, from regional chemical and cellular specializations to macroscale functional networks. Zhang et al....
by Clinical Neuropsychologist Online | Wednesday, November 20, 2024 | Dementia
Abstract Amyloid-PET quantification through the tracer-independent Centiloid (CL) scale has emerged as an essential tool for the accurate measurement of amyloid-β (Aβ) pathology in Alzheimer’s disease (AD) patients. The AMYPAD consortium set out to integrate...
by Clinical Neuropsychologist Online | Tuesday, November 19, 2024 | Dementia
Abstract INTRODUCTION Patterns of signal from tau positron emission tomography (tau-PET) confined to the medial temporal lobe (MTL) or extended into the neocortex may be relevant for Alzheimer’s disease (AD) research if they are linked to differential biomarker...
by Clinical Neuropsychologist Online | Tuesday, November 19, 2024 | Dementia
Abstract INTRODUCTION Progression to Alzheimer’s disease (AD) dementia from normal cognition (NC) can follow different trajectories, with most progressing through a recognizable mild cognitive impairment stage (NC–MCI–AD), while some individuals transition...
by Clinical Neuropsychologist Online | Tuesday, November 19, 2024 | Dementia
Abstract INTRODUCTION Neighborhood environments may promote neurocognitive health in part by providing amenities that encourage physical activity. We examined associations between quantity of walkable facilities, including specifically physical activity facilities...