by Clinical Neuropsychologist Online | Monday, March 11, 2024 | Neuroscience
Nature Neuroscience, Published online: 11 March 2024; doi:10.1038/s41593-024-01606-6Cold sensor identities in peripheral somatosensory neurons remain obscure. We show that GluK2, a kainate-type glutamate-sensing chemoreceptor that mediates synaptic transmission in the...
by Clinical Neuropsychologist Online | Sunday, March 10, 2024 | Dementia
Abstract INTRODUCTION Hypertension and diabetes are modifiable risk factors for dementia. We aimed to assess rural-urban disparities in the diagnosis and treatment of these conditions among aging Indians. METHODS Participants (n = 6316) were from two parallel,...
by Clinical Neuropsychologist Online | Sunday, March 10, 2024 | Dementia
Abstract INTRODUCTION Although dementia-related proteinopathy has a strong negative impact on public health, and is highly heritable, understanding of the related genetic architecture is incomplete. METHODS We applied multidimensional generalized partial credit...
by Clinical Neuropsychologist Online | Saturday, March 9, 2024 | Dementia
Abstract INTRODUCTION The BIN1 coding variant rs138047593 (K358R) is linked to Late-Onset Alzheimer’s Disease (LOAD) via targeted exome sequencing. METHODS To elucidate the functional consequences of this rare coding variant on brain amyloidosis and...
by Clinical Neuropsychologist Online | Saturday, March 9, 2024 | Dementia
Abstract Dementia research lacks appropriate representation of diverse groups who often face substantial adversity and greater risk of dementia. Current research participants are primarily well-resourced, non-Hispanic White, cisgender adults who live close to academic...
