by Clinical Neuropsychologist | Saturday, March 29, 2025 | Dementia
Abstract INTRODUCTION Medicare’s new Guiding an Improved Dementia Experience (GUIDE) model funds integrated dementia care and related caregiver supports for community-living persons with dementia (PwD). Caregiver strain is a factor in provider payment and...
by Clinical Neuropsychologist | Saturday, March 29, 2025 | Dementia
Abstract INTRODUCTION Physical exercise is a primary defense against age-related cognitive decline and Alzheimer’s disease (AD). METHODS We conducted single-nucleus transcriptomic and chromatin accessibility analyses (snRNA-seq and snATAC-seq) on the hippocampus...
by Clinical Neuropsychologist | Saturday, March 29, 2025 | Dementia
Abstract INTRODUCTION Cerebral amyloid angiopathy (CAA) is characterized by the deposition of beta-amyloid (Aβ) in small vessels leading to hemorrhagic stroke and dementia. This study examined whether plasma Aβ42/40, phosphorylated-tau (p-tau), neurofilament light...
by Clinical Neuropsychologist | Saturday, March 29, 2025 | Dementia
Abstract INTRODUCTION Mixed evidence on how statin use affects risk of Alzheimer’s disease and related dementias (ADRD) may reflect heterogeneity across sociodemographic factors. Few studies have sufficient power to evaluate effect modifiers. METHODS Kaiser...
by Clinical Neuropsychologist | Saturday, March 29, 2025 | Dementia
Abstract INTRODUCTION Comorbid conditions associated with Alzheimer’s disease (AD) are poorly understood regarding timing and potential impact on disease onset and progression. METHODS Medical Information Mart for Intensive Care-IV electronic health records from...
by Clinical Neuropsychologist | Saturday, March 29, 2025 | Dementia
Dementia, Ahead of Print. Dementia is a progressive and neurodegenerative condition that leads to a gradual deterioration of the individual’s functional capacity and social relations. Engaging in meaningful activities is considered an effective approach to maintaining...
