Shaping the scientific agenda: Defining and operationalizing brain health in aging

by Clinical Neuropsychologist Online | Thursday, July 16, 2026 | Dementia

Alzheimer’s &Dementia, Volume 22, Issue 7, July 2026. If you do not see content above, kindly GO TO SOURCE. Not all publishers encode content in a way that enables republishing at Neuro.vip. This post is Copyright: | July 16, 2026 Neuro-Dementia Previous...

Deep learning‐based MRI analysis reveals Lewy body co‐pathology accelerates brain aging in Alzheimer’s disease

by Clinical Neuropsychologist Online | Wednesday, July 15, 2026 | Dementia

Abstract INTRODUCTION Lewy body (LB) co-pathology is common in Alzheimer’s disease (AD), yet its in vivo impact on neurodegeneration remains unclear. METHODS We trained a 3D-DenseNet on multi-cohort T1-weighted magnetic resonance imaging (MRI) from cognitively...

Changes in body composition in genetic C9orf72 carriers: The role of the hypothalamus and thalamus

by Clinical Neuropsychologist Online | Wednesday, July 15, 2026 | Dementia

Abstract BACKGROUND Patients with sporadic frontotemporal dementia (FTD) display changes in metabolism and body composition. No studies have examined body composition changes in pre-symptomatic C9orf72 mutation carriers METHODS Asymptomatic C9orf72 expansion carriers...

Age predicts Alzheimer’s in Down syndrome better than MRI, plasma, or cognition

by Clinical Neuropsychologist Online | Tuesday, July 14, 2026 | Dementia

Abstract INTRODUCTION: Alzheimer’s disease (AD) dementia in Down syndrome (DS) occurs at predictable ages. It is unclear whether age can differentiate across AD stages (amyloid positivity, tau positivity, mild cognitive impairment [MCI], dementia). METHODS:...

Structural MRI across lifespan reveals differential thalamic trajectories in Down syndrome

by Clinical Neuropsychologist Online | Tuesday, July 14, 2026 | Dementia

Abstract INTRODUCTION Up to 90% of Down syndrome (DS) patients develop Alzheimer’s disease (AD). Sleep disturbance, affecting over 75% of DS patients, is implicated in AD pathogenesis. The thalamus, central to sleep and arousal, shows early vulnerability in...

Correction to “Systemic piezo1 activation improves cerebrovascular function in Alzheimer’s disease”

by Clinical Neuropsychologist Online | Tuesday, July 14, 2026 | Dementia

Alzheimer’s &Dementia, Volume 22, Issue 7, July 2026. If you do not see content above, kindly GO TO SOURCE. Not all publishers encode content in a way that enables republishing at Neuro.vip. This post is Copyright: | July 14, 2026 Neuro-Dementia Previous...