by Clinical Neuropsychologist Online | Monday, August 24, 2026 | Dementia
Abstract INTRODUCTION Previous works implicate 14 modifiable risk factors as underlying 45% of dementia cases. Population attributable fraction (PAF) is population-specific, limiting generalizability. Little is known about the risk and PAF of dementia in American...
by Clinical Neuropsychologist Online | Monday, August 24, 2026 | Dementia
Dementia, Ahead of Print. Globally, family members account for the main source of caregiving for people with dementia in ordinary housing. Providing informal care may have negative health consequences for relatives such as stress, reduced quality of life and...
by Clinical Neuropsychologist Online | Monday, August 24, 2026 | Dementia
Dementia, Ahead of Print. Dance-based interventions are increasingly recognised as valuable psychosocial approaches to support the wellbeing and social participation of people living with dementia. However, existing research has largely focused on outcomes, with...
by Clinical Neuropsychologist Online | Monday, August 24, 2026 | Dementia
Abstract INTRODUCTION Obesity may increase Alzheimer’s disease (AD) risk, yet the underlying mechanisms remain unclear. METHODS We investigated this link through global epidemiology, Mendelian randomization (MR), transcriptomics, clinical cohort validation, and...
by Clinical Neuropsychologist Online | Saturday, August 22, 2026 | Dementia
Abstract INTRODUCTION Blood-based biomarkers are essential for early detection, monitoring, and therapeutic development in Alzheimer’s disease (AD) and related dementia (ADRD), but current assays lack brain cell specificity and sensitivity to low-abundant...
by Clinical Neuropsychologist Online | Saturday, August 22, 2026 | Dementia
Abstract INTRODUCTION SORL1 encodes the sorting receptor SORLA, a major genetic contributor to Alzheimer’s disease (AD). Although SORL1 loss disrupts endosomal trafficking and promotes amyloidogenic amyloid precursor protein (APP) processing, the functional...
