Changing care practices and culture in a specialised unit for people with behavioural and psychological symptoms of dementia

by Clinical Neuropsychologist | Friday, April 11, 2025 | Dementia

Dementia, Ahead of Print. There are significant challenges in creating and maintaining positive care cultures for people with dementia. My Home Life is a UK initiative that provides staff with frameworks and tools to facilitate the development and implementation of...

Impact evaluation of a dementia-friendly community mural: Planting a seed for change

by Clinical Neuropsychologist | Friday, April 11, 2025 | Dementia

Dementia, Ahead of Print. Stigma against persons living with dementia negatively impacts their quality of life. One of the aims of dementia-friendly community initiatives is to reconstruct public perceptions of dementia through dementia awareness campaigns. In this...

Amyloid precursor protein and presenilin‐1 knock‐in immunodeficient mice exhibit intraneuronal Aβ pathology, microgliosis, and extensive neuronal loss

by Clinical Neuropsychologist | Tuesday, April 8, 2025 | Dementia

Abstract INTRODUCTION Transgenic mice overexpressing familial Alzheimer’s disease (AD) mutations (FAD) show non-physiological traits, and their immunocompetent backgrounds limit their use in AD immunotherapy research. Preclinical models that reflect human immune...

Tauopathy after long‐term cervical lymphadenectomy

by Clinical Neuropsychologist | Monday, April 7, 2025 | Dementia

Abstract INTRODUCTION This study examined the effects of long-term cervical lymphadenectomy (cLE) on cognitive and Alzheimer’s disease (AD)–like tauopathy changes. METHODS Male C57BL/6 mice were used to assess cLE impacts on sleep, brain pathways, and...

A multiperspective investigation of the underrepresentation of minoritized ethnic participants in dementia research and proposed strategies to improve inclusive recruitment practices

by Clinical Neuropsychologist | Monday, April 7, 2025 | Dementia

Abstract INTRODUCTION Minoritized ethnic populations are underrepresented in dementia research despite having differing risk and prognosis profiles. We sought to gain multiperspective insights about why minoritized ethnic groups are underrepresented in dementia...

Neighborhood disadvantage and the incidence of dementia in US Black women

by Clinical Neuropsychologist | Monday, April 7, 2025 | Dementia

Abstract INTRODUCTION We investigated the association of neighborhood disadvantage with the incidence of Alzheimer’s disease and related dementias (ADRD) in the longitudinal Black Women’s Health Study (BWHS). METHODS The study included 10,915 BWHS...