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Predicting Alzheimer’s disease subtypes and understanding their molecular characteristics in living patients with transcriptomic trajectory profiling

by Clinical Neuropsychologist | Wednesday, January 15, 2025 | Dementia

Abstract INTRODUCTION Deciphering the diverse molecular mechanisms in living Alzheimer’s disease (AD) patients is a big challenge but is pivotal for disease prognosis and precision medicine development. METHODS Utilizing an optimal transport approach, we...

Multimodal imaging of murine cerebrovascular dynamics induced by transcranial pulse stimulation

by Clinical Neuropsychologist | Tuesday, January 14, 2025 | Dementia

Abstract INTRODUCTION Transcranial pulse stimulation (TPS) is increasingly being investigated as a promising potential treatment for Alzheimer’s disease (AD). Although the safety and preliminary clinical efficacy of TPS short pulses have been supported by...

Response to the letter titled “Analysis of semaglutide’s effect on Alzheimer’s disease risk”

by Clinical Neuropsychologist | Tuesday, January 14, 2025 | Dementia

Alzheimer’s &Dementia, EarlyView. If you do not see content above, kindly GO TO SOURCE. Not all publishers encode content in a way that enables republishing at Neuro.vip. This post is Copyright: Rong Xu | January 14, 2025 Wiley: Alzheimer’s &...

Clinical criteria for limbic‐predominant age‐related TDP‐43 encephalopathy

by Clinical Neuropsychologist | Tuesday, January 14, 2025 | Dementia

Abstract Limbic predominant age-related TDP-43 encephalopathy neuropathologic change (LATE-NC) is highly prevalent in late life and a common co-pathology with Alzheimer’s disease neuropathologic change (ADNC). LATE-NC is a slowly progressive, amnestic clinical...

An evaluation of a community dementia screening program in rural Kenya: DEM‐SKY

by Clinical Neuropsychologist | Tuesday, January 14, 2025 | Dementia

Abstract INTRODUCTION This study describes the implementation outcomes and evaluation of DEM-SKY, a community-based dementia screening program developed in rural Kenya with the support of community health care workers (CHWs). METHODS DEM-SKY was delivered to 3546...

Clinical utility of plasma p‐tau217 in identifying abnormal brain amyloid burden in an Asian cohort with high prevalence of concomitant cerebrovascular disease

by Clinical Neuropsychologist | Tuesday, January 14, 2025 | Dementia

Abstract INTRODUCTION Using an Asian cohort with high prevalence of concomitant cerebrovascular disease (CeVD), we evaluated the performance of a plasma immunoassay for tau phosphorylated at threonine 217 (p-tau217) in detecting amyloid beta positivity (Aβ+) on...
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