Studying What Matters: South Texas Community-Driven Dementia Research Priorities

by Clinical Neuropsychologist Online | Tuesday, August 25, 2026 | Dementia

Dementia, Ahead of Print. South Texas has among the highest dementia prevalence rates in the United States, yet communities in the region remain consistently underrepresented in dementia research. Aligning research studies with what matters to communities most...

Disruption of hippocampal upstream regulators of mTOR and insulin pathways in Down syndrome with Alzheimer’s disease neuropathology: Preliminary observations

by Clinical Neuropsychologist Online | Monday, August 24, 2026 | Dementia

Abstract INTRODUCTION Down syndrome (DS) is caused by a complete or partial trisomy of chromosome 21, resulting in variable intellectual disabilities and a high risk for early-onset Alzheimer’s disease (DS-AD). Dysregulation of the mammalian target of rapamycin...

Risk factors and population attributable fraction for dementia in American Indians: The Strong Heart Study

by Clinical Neuropsychologist Online | Monday, August 24, 2026 | Dementia

Abstract INTRODUCTION Previous works implicate 14 modifiable risk factors as underlying 45% of dementia cases. Population attributable fraction (PAF) is population-specific, limiting generalizability. Little is known about the risk and PAF of dementia in American...

Family Members Experiences of Being Identified as a Family Caregiver to a Person Living With Dementia

by Clinical Neuropsychologist Online | Monday, August 24, 2026 | Dementia

Dementia, Ahead of Print. Globally, family members account for the main source of caregiving for people with dementia in ordinary housing. Providing informal care may have negative health consequences for relatives such as stress, reduced quality of life and...

Understanding Dance Facilitation in Dementia Care: A Qualitative Study Using Socio-Ecological-Relational Framework

by Clinical Neuropsychologist Online | Monday, August 24, 2026 | Dementia

Dementia, Ahead of Print. Dance-based interventions are increasingly recognised as valuable psychosocial approaches to support the wellbeing and social participation of people living with dementia. However, existing research has largely focused on outcomes, with...

Multi‐omics identification of haptoglobin as a novel target for increased Alzheimer’s disease risk associated with obesity through inhibiting the phagocytosis of Aβ by disease‐associated microglia

by Clinical Neuropsychologist Online | Monday, August 24, 2026 | Dementia

Abstract INTRODUCTION Obesity may increase Alzheimer’s disease (AD) risk, yet the underlying mechanisms remain unclear. METHODS We investigated this link through global epidemiology, Mendelian randomization (MR), transcriptomics, clinical cohort validation, and...